38 people, including two 17-year-olds and a 15-year old have now been arrested following a protest in the CBD this morning.
More than 100 activists blocked the Flinders- Swanston St intersection this morning, some sitting on tram tracks, calling for animal liberation this morning.
Protesters held signs that held: "This is a peaceful protest" and "SOS animal emergency climate emergency".
Three vehicles were used to block the intersection of Flinders and Swanston streets, with a number of people chaining themselves to the vehicles. The vehicles have now been towed and the scene has been cleared.
Police say the protesters have been arrested in relation to obstructing a roadway, resisting or obstructing police, and are assisting police with their enquiries.
Superintendent David Clayton said the lack of prior engagement with police from the protesters was disappointing and also caused considerable disruptions to thousands of people attempting to navigate through the CBD during peak hour.
"There will be people who couldn't access services during this time," Supt Clayton said.
“The safety and security of the community is Victoria Police’s number one priority.
They said police were not spoken to prior to the protest.
“This lack of engagement puts the entire community at risk with road closures and delays to transport services.
“We respect the right for people to protest peacefully but we will not tolerate anti-social behaviour that disrupts the broader community.”
Police have monitored a number of other protests at locations state-wide, including Bacchus Marsh, Laverton North, Pakenham and Corio.
Officers are also monitoring a protest at the aquarium, where protesters have blocked the main entrance.